Description

2-Acetamido-1,3,6-Tri-o-Acetyl-4-Deoxy-4-Fluoroglucopyranose is a key fluorinated carbohydrate derivative, serving as a crucial synthetic intermediate in advanced organic and medicinal chemistry. Its value lies in the strategic introduction of a fluorine atom at the 4-position, which is instrumental for modulating the biological activity and metabolic stability of target molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel glycosidase inhibitors, antiviral agents, and diagnostic probes.

Application

• Pharmaceutical Intermediate: A vital building block for synthesizing fluorinated nucleoside analogs and other bioactive molecules with potential antiviral or anticancer properties.
• Glycobiology Research: Used in the study of enzyme mechanisms, particularly for probing the active sites of glycosidases and glycosyltransferases through fluorine substitution.
• Diagnostic Probe Development: Serves as a precursor for 18F-labeled compounds used in Positron Emission Tomography (PET) imaging.
• Chemical Biology Tool: Employed to create fluorinated sugar mimics for investigating carbohydrate-protein interactions and metabolic pathways.
• Agrochemical Research: Potential intermediate in the synthesis of novel fluorinated pesticides or plant growth regulators.

Basic Information

Product Name	2-Acetamido-1,3,6-Tri-o-Acetyl-4-Deoxy-4-Fluoroglucopyranose
CAS No.	129785-44-0
Molecular Formula	C14H20FNO8
Molecular Weight	349.31 g/mol
Synonyms	4-Deoxy-4-fluoro-N-acetylglucosamine tetraacetate; 1,3,6-Tri-O-acetyl-2-acetamido-2,4-dideoxy-4-fluoro-D-glucopyranose; 4-Fluoro-2-acetamido-1,3,6-tri-O-acetyl-2,4-dideoxy-D-glucopyranose; 4-Fluoro-N-acetylglucosamine tetraacetate; 2-Acetamido-1,3,6-tri-O-acetyl-4-deoxy-4-fluoro-D-glucopyranose; 4-Fluoro-GlcNAc tetraacetate; Fluorinated GlcNAc derivative
EINECS	Contact for details

Quality Control

Our 2-Acetamido-1,3,6-Tri-o-Acetyl-4-Deoxy-4-Fluoroglucopyranose is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, verified by techniques including HPLC, NMR, and MS. We support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.