Description

1-((Benzyloxy)Carbonyl)-5-Methylpiperidine-2-Carboxylic Acid is a high-purity, protected amino acid derivative that serves as a critical chiral building block in advanced organic synthesis. This compound is essential for pharmaceutical research and development, enabling the precise construction of complex molecular architectures. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of novel active pharmaceutical ingredients (APIs) and peptide-based therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder therapeutics.
• Peptide Chemistry: Used as a protected amino acid derivative for solid-phase and solution-phase peptide synthesis, facilitating the creation of complex peptide sequences.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for studying biological pathways and target engagement.
• Asymmetric Synthesis: Serves as a starting material or intermediate in catalytic asymmetric reactions to introduce stereogenic centers with high enantiomeric purity.
• Process Chemistry Development: Used in route scouting and optimization for the scalable manufacturing of active pharmaceutical ingredients (APIs).
• Custom Synthesis & Contract Manufacturing: A fundamental component for CDMOs (Contract Development and Manufacturing Organizations) offering bespoke chemical synthesis services.

Basic Information

Product Name	1-((Benzyloxy)Carbonyl)-5-Methylpiperidine-2-Carboxylic Acid
CAS No.	129769-20-6
Molecular Formula	C15H19NO4
Molecular Weight	277.32 g/mol
Synonyms	5-Methyl-1-CBz-pipecolic Acid; 1-Cbz-5-Methylpipecolic Acid; 1-[(Benzyloxy)carbonyl]-5-methylpiperidine-2-carboxylic acid; (2S)-1-[(Benzyloxy)carbonyl]-5-methylpiperidine-2-carboxylic acid; (R)-1-Cbz-5-Methyl-2-piperidinecarboxylic Acid; N-Carbobenzyloxy-5-methyl-D-pipecolic Acid; N-Cbz-5-Methylpipecolic Acid; 1-N-CBZ-5-METHYLPIPECOLIC ACID
EINECS	Contact for details

Quality Control

Our 1-((Benzyloxy)Carbonyl)-5-Methylpiperidine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.