Description

4-(2-Chloro-1,1,2-trifluoroethoxy)-2-methyl-phenol is a specialized fluorinated phenolic compound that serves as a critical building block in advanced chemical synthesis. Its unique structure, featuring a trifluoroethoxy side chain, provides valuable properties for creating high-performance materials and active pharmaceutical ingredients. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with enhanced stability and bioactivity.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms can improve metabolic stability and efficacy.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated compounds for electronic display applications.
• Polymer Modification: Acts as a functional monomer or additive to impart specific properties like chemical resistance or low surface energy to polymers.
• Organic Synthesis Building Block: Employed in cross-coupling reactions and other organic transformations to introduce the (2-chloro-1,1,2-trifluoroethoxy)phenol moiety.
• Research & Development: A valuable tool for medicinal chemistry and material science research exploring structure-activity relationships.

Basic Information

Product Name	4-(2-Chloro-1,1,2-trifluoroethoxy)-2-methyl-phenol
CAS No.	129670-05-9
Molecular Formula	C9H8ClF3O2
Molecular Weight	240.61 g/mol
Synonyms	2-Methyl-4-(2-chloro-1,1,2-trifluoroethoxy)phenol; 4-(2-Chloro-1,1,2-trifluoroethoxy)-o-cresol; 2-Methyl-4-(β,β,β-trifluoro-α-chloroethoxy)phenol; Phenol, 4-(2-chloro-1,1,2-trifluoroethoxy)-2-methyl-; 2-Methyl-4-(1,1,2-trifluoro-2-chloroethoxy)phenol
EINECS	Contact for details

Quality Control

Our 4-(2-Chloro-1,1,2-trifluoroethoxy)-2-methyl-phenol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports your R&D and production needs with reliable, high-purity intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.