Description

2-(4-Allyl-1-Piperazinyl)-4-Butoxyquinazoline Fumarate (2:3) is a high-purity, non-stoichiometric salt complex of a quinazoline derivative, designed for advanced research and development applications. This compound is valued for its specific molecular architecture, which is critical for investigating structure-activity relationships in pharmaceutical discovery. It serves as a key synthetic intermediate or reference standard for researchers in medicinal chemistry and pharmacology, particularly those focused on central nervous system (CNS) targets and receptor modulation.

Application

• Pharmaceutical R&D Intermediate: Serves as a crucial building block in the synthesis of novel therapeutic candidates, particularly for neurological and psychiatric disorders.
• Medicinal Chemistry Reference Standard: Used as a high-purity standard for analytical method development, validation, and quality control in drug discovery pipelines.
• Biochemical Research: Employed in in vitro studies to explore interactions with specific enzyme systems or receptor subtypes relevant to its pharmacophore.
• Academic Research: Utilized in university and institutional labs for fundamental research into heterocyclic chemistry and drug-receptor kinetics.
• Process Chemistry Development: Acts as a model compound for scaling up synthetic routes and optimizing purification processes in pre-clinical development.

Basic Information

Product Name	2-(4-Allyl-1-Piperazinyl)-4-Butoxyquinazoline Fumarate (2:3)
CAS No.	129663-99-6
Molecular Formula	C19H26N4O • 1.5 C4H4O4
Molecular Weight	~ 574.62 g/mol (for the 2:3 salt complex)
Synonyms	4-Butoxy-2-(4-allyl-1-piperazinyl)quinazoline fumarate (2:3); 2-(4-Allylpiperazin-1-yl)-4-butoxyquinazoline fumarate (2:3); Quinazoline, 2-(4-allyl-1-piperazinyl)-4-butoxy-, (E)-2-butenedioate (2:3); 129663-99-6; UNII-8V3Y0F2V7F
EINECS	Contact for details

Quality Control

Our 2-(4-Allyl-1-Piperazinyl)-4-Butoxyquinazoline Fumarate (2:3) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.