Description

Acetamide, n-(3,3,3-Trifluoro-1-Methyl-2-Oxopropyl)- is a specialized fluorinated acetamide derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity imparted by the trifluoromethyl and oxopropyl groups, enabling the construction of complex molecules with tailored properties. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing next-generation active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs to enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the introduction of fluorine atoms improves efficacy and environmental profile.
• Material Science Research: Serves as a precursor for fluorinated polymers, coatings, and liquid crystals, contributing to materials with unique surface, optical, or thermal properties.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for studying biological mechanisms and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	Acetamide, n-(3,3,3-Trifluoro-1-Methyl-2-Oxopropyl)-
CAS No.	129660-27-1
Molecular Formula	C7H10F3NO2
Molecular Weight	197.16 g/mol
Synonyms	1,1,1-Trifluoro-2-(acetylamino)-3-butanone; 3-(Acetylamino)-4,4,4-trifluoro-2-butanone; 4,4,4-Trifluoro-3-oxo-N-acetylbutan-1-amine; N-Acetyl-4,4,4-trifluoro-3-oxobutan-1-amine; TFAAK (common abbreviation); Trifluoroacetoacetamide derivative; N-(3,3,3-Trifluoro-1-methyl-2-oxopropyl)acetamide
EINECS	Contact for details

Quality Control

Our Acetamide, n-(3,3,3-Trifluoro-1-Methyl-2-Oxopropyl)- is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting key parameters such as assay and impurity profiles. Our quality commitment supports applications requiring high-purity intermediates for GMP or research-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.