Description

(2S,3S)-3-Amino-2-Hydroxy-4-Phenylbutyric Acid Hydrochloride is a high-purity, non-natural amino acid derivative and a key chiral building block in organic synthesis. This compound is essential for the development of advanced pharmaceutical intermediates, particularly in the synthesis of protease inhibitors and other bioactive molecules. It is primarily utilized by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers requiring high stereochemical purity for critical synthetic pathways.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of HIV protease inhibitors and other antiviral agents.
• Peptide Synthesis: Used in the preparation of complex, stereochemically defined peptides for drug discovery and biochemical research.
• Asymmetric Catalysis Research: Serves as a precursor or ligand in the development of novel chiral catalysts.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and the creation of targeted molecular libraries.
• Reference Standard: Used as a high-purity analytical standard for quality control in pharmaceutical manufacturing.
• Bioconjugation: The functional groups allow for its use in creating targeted drug conjugates and bioprobes.

Basic Information

Product Name	(2S,3S)-3-Amino-2-Hydroxy-4-Phenylbutyric Acid Hydrochloride
CAS No.	129593-20-0
Molecular Formula	C10H14ClNO3
Molecular Weight	231.68 g/mol
Synonyms	(2S,3S)-AHPA-HCl; (2S,3S)-3-Amino-2-hydroxy-4-phenylbutanoic acid hydrochloride; (2S,3S)-AHPBA-HCl; (3S)-3-Amino-(2S)-2-hydroxy-4-phenylbutyric acid hydrochloride; L-AHPBA hydrochloride; (2S,3S)-3-Amino-2-hydroxy-4-phenylbutyrate hydrochloride; (2S,3S)-3-Amino-2-hydroxy-4-phenylbutanoate hydrochloride
EINECS	Contact for details

Quality Control

Our (2S,3S)-3-Amino-2-Hydroxy-4-Phenylbutyric Acid Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% de
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.