Description

n-(2,3-Dimethyl-5-Oxo-1-Phenyl-2,5-Dihydro-1H-Pyrazol-4-Yl)-2,2,2-Trifluoroacetamide is a high-purity, specialized heterocyclic compound featuring a pyrazolone core functionalized with a trifluoroacetamide group. This structure makes it a critical advanced intermediate in the synthesis of complex active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily required by pharmaceutical R&D and manufacturing sectors for developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting inflammation or central nervous system disorders.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides due to its unique trifluoromethylated structure.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing complex heterocyclic frameworks in academic and industrial research laboratories.
• Material Science: Potential intermediate for specialty polymers or functional materials requiring specific fluorinated motifs.

Basic Information

Product Name	n-(2,3-Dimethyl-5-Oxo-1-Phenyl-2,5-Dihydro-1H-Pyrazol-4-Yl)-2,2,2-Trifluoroacetamide
CAS No.	129476-61-5
Molecular Formula	C13H12F3N3O2
Molecular Weight	299.25 g/mol
Synonyms	2,2,2-Trifluoro-N-(2,3-dimethyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-4-yl)acetamide; 4-(Trifluoroacetylamino)-2,3-dimethyl-1-phenyl-5-pyrazolone; 1-Phenyl-2,3-dimethyl-4-trifluoroacetamido-5-pyrazolone; 4-Amino-1-phenyl-2,3-dimethyl-5-pyrazolone trifluoroacetamide derivative; Antipyrine trifluoroacetamide derivative; TFAP
EINECS	Contact for details

Quality Control

Our production of n-(2,3-Dimethyl-5-Oxo-1-Phenyl-2,5-Dihydro-1H-Pyrazol-4-Yl)-2,2,2-Trifluoroacetamide adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. The compound may be moisture-sensitive; handle and store under inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.