Description

Methyl-2-Deoxy-5-o-(4-Phenylbenzoyl)-α-D-Threo-Pentofuranoside is a specialized nucleoside derivative and a key protected intermediate in synthetic organic chemistry. This compound is critical for researchers and manufacturers requiring high-purity building blocks for the synthesis of complex bioactive molecules. It is primarily utilized in the development of novel antiviral agents, modified oligonucleotides, and other pharmaceutical candidates where precise stereochemistry and functional group protection are essential.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of nucleoside-based antiviral and anticancer prodrugs.
• Oligonucleotide Synthesis: Used in the preparation of modified DNA/RNA analogs for research, diagnostics, and therapeutic applications.
• Medicinal Chemistry Research: Acts as a protected scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Bioconjugation: Provides a functional handle for attaching reporter groups or other molecules in bioconjugate chemistry.
• Process Chemistry Development: Employed in scaling up synthetic routes for active pharmaceutical ingredients (APIs) under GMP conditions.
• Academic & Institutional Research: A valuable reagent for exploring new synthetic methodologies and carbohydrate chemistry.

Basic Information

Product Name	Methyl-2-Deoxy-5-o-(4-Phenylbenzoyl)-α-D-Threo-Pentofuranoside
CAS No.	129468-50-4
Molecular Formula	C20H20O6
Molecular Weight	356.37 g/mol
Synonyms	Methyl 2-deoxy-5-O-(4-phenylbenzoyl)-α-D-threo-pentofuranoside; α-D-Threo-Pentofuranoside, methyl 2-deoxy-5-O-(4-phenylbenzoyl)-; Methyl 2-deoxy-5-O-(p-phenylbenzoyl)-α-D-threo-pentofuranoside; 5-O-(4-Biphenylcarbonyl)-2-deoxy-α-D-threo-pentofuranoside methyl ester; Protected D-Threose Derivative; 4-Phenylbenzoyl-protected Nucleoside Intermediate
EINECS	Contact for details

Quality Control

Our Methyl-2-Deoxy-5-o-(4-Phenylbenzoyl)-α-D-Threo-Pentofuranoside is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support cGMP compliance for advanced intermediates and can provide material for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic; handle and store under an inert atmosphere such as nitrogen or argon for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.