Description

n-Boc-D-Tyrosine Benzyl Ester is a protected, non-natural amino acid derivative of significant importance in advanced organic synthesis. This compound serves as a critical chiral building block for the construction of complex peptides and peptidomimetics, offering precise stereochemical control. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of therapeutic agents, enzyme inhibitors, and novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate D-tyrosine residues with orthogonal protecting groups (Boc for amine, benzyl for carboxylic acid).
• Protease Inhibitor Development: Serves as a core structure for designing inhibitors targeting specific proteases and enzymes.
• Chemical Biology Research: Employed in the study of protein-protein interactions and the creation of labeled or modified peptides for diagnostic and research purposes.
• Asymmetric Synthesis: Utilized as a starting material or auxiliary in asymmetric catalytic reactions to induce chirality in target molecules.

Basic Information

Product Name	n-Boc-D-Tyrosine Benzyl Ester
CAS No.	129439-63-0
Molecular Formula	C21H25NO5
Molecular Weight	371.43 g/mol
Synonyms	Boc-D-Tyr-OBzl; (R)-2-((tert-Butoxycarbonyl)amino)-3-(4-hydroxyphenyl)propionic acid benzyl ester; Benzyl (R)-2-[(tert-butoxycarbonyl)amino]-3-(4-hydroxyphenyl)propanoate; D-Tyrosine, N-[(1,1-dimethylethoxy)carbonyl]-, benzyl ester; Boc-D-Tyrosine benzyl ester; N-Boc-D-Tyrosine O-benzyl ester; tert-Butoxycarbonyl-D-tyrosine benzyl ester
EINECS	Contact for details

Quality Control

Our n-Boc-D-Tyrosine Benzyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic identification. A Certificate of Analysis (COA) detailing all specifications is provided to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is sensitive to strong acids and should be kept away from such conditions. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.