Description

Boc-Dl-7-Azatryptophan is a protected derivative of the non-proteinogenic amino acid 7-azatryptophan, featuring a tert-butoxycarbonyl (Boc) protecting group on the α-amino functionality. This compound is a crucial building block in peptide synthesis and medicinal chemistry research, enabling the controlled incorporation of the unique 7-azaindole moiety into molecular architectures. It is primarily utilized by research scientists and process development chemists in the pharmaceutical, biotechnology, and agrochemical sectors for the development of novel bioactive compounds and chemical probes.

Application

• Peptide Synthesis Intermediate: Serves as a key protected amino acid for solid-phase and solution-phase peptide synthesis (SPPS), allowing for the introduction of the 7-azatryptophan residue.
• Medicinal Chemistry & Drug Discovery: Used in the research and development of novel drug candidates, particularly those targeting protein-protein interactions or enzymes where the azaindole scaffold is pharmacologically relevant.
• Chemical Biology Research: Employed in the synthesis of labeled peptides or modified proteins for studying biological structure, function, and mechanisms.
• Agrochemical Research: Acts as a specialty intermediate in the design and synthesis of new active ingredients with potential herbicidal or insecticidal properties.
• Bioconjugation: Useful for creating custom linkers or modified biomolecules for diagnostic assays or targeted delivery systems.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in related synthetic processes.

Basic Information

Product Name	Boc-Dl-7-Azatryptophan
CAS No.	129423-33-2
Molecular Formula	C₁₇H₂₁N₃O₄
Molecular Weight	331.37 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-7-azatryptophan; Boc-7-Azatryptophan; N-Boc-7-azatryptophan; DL-1-(1H-Pyrrolo[2,3-b]pyridin-3-yl)-2-[(tert-butoxycarbonyl)amino]propanoic Acid; (RS)-2-[(tert-Butoxycarbonyl)amino]-3-(1H-pyrrolo[2,3-b]pyridin-3-yl)propanoic Acid; tert-Butyl (1-(1H-pyrrolo[2,3-b]pyridin-3-yl)-1-carboxyethyl)carbamate; 7-Azatryptophan, N-Boc-protected
EINECS	Contact for details

Quality Control

Our Boc-Dl-7-Azatryptophan is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and spectroscopic identification (NMR, IR, MS), to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (DL Ratio)	~50:50 (Racemic)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.