Description

19,19-Difluoroandrost-4-En-17-One is a high-purity, synthetic steroid derivative characterized by the strategic introduction of fluorine atoms at the 19-position. This fluorinated modification is of significant interest in advanced pharmaceutical research and development, particularly for its potential to alter metabolic stability, bioavailability, and receptor binding affinity. It serves as a critical pharmaceutical intermediate and a valuable reference standard for researchers in medicinal chemistry, steroid pharmacology, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel fluorinated steroid-based drugs, including potential anti-inflammatory, anti-androgenic, or anabolic agents.
• Medicinal Chemistry Research: Used to study structure-activity relationships (SAR) and the effects of fluorination on steroid hormone receptor interaction and metabolic pathways.
• Reference Standard: Serves as an analytical standard in quality control laboratories for method development, validation, and impurity profiling of related steroid compounds.
• Biochemical Tool Compound: Employed in preclinical studies to investigate steroidogenesis, enzyme inhibition, and specific biological mechanisms.
• Academic & Institutional Research: Utilized by universities and research institutes for fundamental studies in organic synthesis and steroid chemistry.

Basic Information

Product Name	19,19-Difluoroandrost-4-En-17-One
CAS No.	129400-04-0
Molecular Formula	C₁₉H₂₆F₂O
Molecular Weight	308.41 g/mol
Synonyms	19,19-Difluoroandrost-4-en-17-one; 17-Oxo-19,19-difluoroandrost-4-ene; 19,19-Difluoro-4-androsten-17-one; Androst-4-ene-17-one, 19,19-difluoro-; 19,19-Difluoroandrost-4-en-17-one (CAS 129400-04-0); 19,19-Difluoro-δ⁴-androsten-17-one
EINECS	Contact for details

Quality Control

Our 19,19-Difluoroandrost-4-En-17-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.