Description

Boc-Cys(4-Mebzl)-Ol CAS NO 129397-85-9 is a protected cysteine derivative, specifically an amino acid building block where the thiol group is protected by a 4-methylbenzyl (4-Mebzl) group and the amine is protected by a tert-butyloxycarbonyl (Boc) group. This compound is critical for the controlled synthesis of peptides and proteins, preventing unwanted side reactions during coupling steps. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors for solid-phase peptide synthesis (SPPS) and the development of novel therapeutic peptides.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid building block for the sequential assembly of complex peptides.
• Pharmaceutical Research: Used in the discovery and development of peptide-based drugs, including hormones, antibiotics, and enzyme inhibitors.
• Bioconjugation: The protected thiol group allows for site-specific modification of peptides and proteins after deprotection.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening of bioactive peptide sequences.
• Chemical Biology Studies: Essential for synthesizing custom peptides used as probes to study protein function and interaction.
• Intermediate for Cysteine-Containing Peptides: Crucial for the reliable incorporation of cysteine residues, which are vital for disulfide bridge formation and protein stability.

Basic Information

Product Name	Boc-Cys(4-Mebzl)-Ol
CAS No.	129397-85-9
Molecular Formula	C16H23NO4S
Molecular Weight	325.42 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-S-(4-methylbenzyl)-L-cysteine; Boc-Cys(4-MeBzl)-OH; Boc-S-(4-methylbenzyl)-L-cysteine; (2R)-2-[(tert-Butoxycarbonyl)amino]-3-[(4-methylphenyl)methyl]sulfanyl]propanoic acid; Boc-L-Cys(4-MeBzl)-OH; N-Boc-S-(p-methylbenzyl)-L-cysteine; Boc-Cys(Mob)-OH; Boc-S-p-methylbenzyl-L-cysteine
EINECS	Contact for details

Quality Control

Our Boc-Cys(4-Mebzl)-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for peptide synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and other relevant methods is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	-15.0° to -25.0° (c=1 in DMF)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.