Description

(R)-6-(Phenethyl-Propyl-Amino)-5,6,7,8-Tetrahydro-Naphthalen-1-Ol Hydrochloride is a high-purity chiral amine derivative and a key pharmaceutical intermediate. This compound matters for its role in the synthesis of complex active pharmaceutical ingredients (APIs), where its defined stereochemistry is critical for biological activity. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within the central nervous system (CNS) and cardiovascular domains.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel APIs, especially those targeting neurological and cardiovascular receptors.
• Chiral Synthesis: Used in asymmetric synthesis and medicinal chemistry research to introduce a specific stereogenic center into target molecules.
• Biochemical Research: Serves as a reference standard or a precursor in pharmacological studies and assay development.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for exploring new synthetic pathways and structure-activity relationships (SAR).

Basic Information

Product Name	(R)-6-(Phenethyl-Propyl-Amino)-5,6,7,8-Tetrahydro-Naphthalen-1-Ol Hydrochloride
CAS No.	129389-27-1
Molecular Formula	C21H30ClNO
Molecular Weight	347.92 g/mol
Synonyms	(R)-6-(N-Phenethyl-N-propylamino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride; (R)-6-(Phenethylpropylamino)-1,2,3,4-tetrahydro-1-naphthol hydrochloride; (R)-6-(2-Phenylethyl)(propyl)amino-5,6,7,8-tetrahydro-1-naphthalenol hydrochloride; (R)-N-Phenethyl-N-propyl-5,6,7,8-tetrahydro-1-naphthylamine hydrochloride; (R)-1-Hydroxy-6-(phenethylpropylamino)tetralin hydrochloride; R-6-PPAT hydrochloride; CAS 129389-27-1
EINECS	Contact for details

Quality Control

Our (R)-6-(Phenethyl-Propyl-Amino)-5,6,7,8-Tetrahydro-Naphthalen-1-Ol Hydrochloride is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity, to ensure compliance with stringent specifications for pharmaceutical intermediates. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.