Description

(R)-1-(2-Methyl-1,3-Dioxolan-2-Yl)-n-(1-Phenylethyl)Cyclopropanecarboxamide CAS NO 129321-57-9 is a high-value, chiral cyclopropane derivative featuring a protected carbonyl group and a stereogenic center. This compound is a critical synthetic intermediate in the production of advanced pharmaceutical active ingredients, particularly those targeting central nervous system disorders. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics, where its defined stereochemistry is essential for biological activity.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of complex drug molecules, especially for neurological and psychiatric applications.
• Asymmetric Synthesis: Used in stereoselective reactions to construct molecules with high enantiomeric purity for preclinical and clinical research.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Employed in the scale-up and route scouting for the commercial manufacturing of target APIs.
• Reference Standard: Used as an analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	(R)-1-(2-Methyl-1,3-Dioxolan-2-Yl)-n-(1-Phenylethyl)Cyclopropanecarboxamide
CAS No.	129321-57-9
Molecular Formula	C18H25NO3
Molecular Weight	303.40 g/mol
Synonyms	(R)-1-(2-Methyl-1,3-dioxolan-2-yl)-N-(1-phenylethyl)cyclopropanecarboxamide; (R)-N-(1-Phenylethyl)-1-(2-methyl-1,3-dioxolan-2-yl)cyclopropanecarboxamide; Cyclopropanecarboxamide, 1-(2-methyl-1,3-dioxolan-2-yl)-N-[(1R)-1-phenylethyl]-; (R)-N-(α-Methylbenzyl)-1-(2-methyl-1,3-dioxolan-2-yl)cyclopropanecarboxamide; (R)-N-(1-Phenylethyl)-1-(2-methyl-1,3-dioxolane-2-yl)cyclopropanecarboxamide
EINECS	Contact for details

Quality Control

Our (R)-1-(2-Methyl-1,3-Dioxolan-2-Yl)-n-(1-Phenylethyl)Cyclopropanecarboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.