Description

(7S)-5-Azaspiro[2.4]Heptan-7-Amine is a high-purity, chiral spirocyclic amine building block of significant interest in advanced organic synthesis. Its unique constrained spirocyclic structure makes it a valuable intermediate for constructing complex molecules with specific three-dimensional architectures. This compound is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, especially in neuroscience and psychiatry.
• Medicinal Chemistry: Used to introduce a rigid, spirocyclic amine moiety into lead compounds to modulate bioavailability, potency, and selectivity.
• Agrochemical Synthesis: Serves as a building block for creating novel pesticides and herbicides with potentially improved efficacy.
• Ligand and Catalyst Development: Employed in the design of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Useful for creating molecular probes to study enzyme function and biological pathways.
• Academic and Industrial R&D: A valuable reagent for methodological studies in organic synthesis and the exploration of new chemical space.

Basic Information

Product Name	(7S)-5-Azaspiro[2.4]Heptan-7-Amine
CAS No.	129306-12-3
Molecular Formula	C6H12N2
Molecular Weight	112.17 g/mol
Synonyms	(7S)-5-Azaspiro[2.4]heptan-7-amine; (7S)-5-Azaspiro[2.4]heptane-7-amine; (S)-5-Azaspiro[2.4]heptan-7-amine; (S)-5-Azaspiro[2.4]heptane-7-amine; (7S)-5-Aza-spiro[2.4]heptan-7-ylamine; (S)-5-Aza-spiro[2.4]heptan-7-ylamine; (7S)-7-Amino-5-azaspiro[2.4]heptane; (S)-7-Amino-5-azaspiro[2.4]heptane
EINECS	Contact for details

Quality Control

Our (7S)-5-Azaspiro[2.4]Heptan-7-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications for identity, purity, and enantiomeric excess are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.