Description

1-Pyrrolidinecarboxamide,3-Mercapto-,(S)-(9Ci) is a chiral, sulfur-containing pyrrolidine derivative of significant interest in advanced organic synthesis. This compound matters as a versatile building block for constructing complex molecular architectures, particularly in the development of pharmaceuticals and bioactive molecules. It is primarily needed by research institutions and industrial R&D departments focused on medicinal chemistry, asymmetric synthesis, and the creation of novel enzyme inhibitors or receptor modulators.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for neurological and metabolic disorders.
• Asymmetric Catalyst Ligand Precursor: Used in the synthesis of specialized ligands for metal-catalyzed asymmetric reactions, enabling the production of enantiomerically pure compounds.
• Protease Inhibitor Scaffold: The mercapto and carboxamide functional groups make it a valuable core structure for designing cysteine protease inhibitors.
• Peptidomimetics Research: Acts as a proline analog for creating modified peptides with enhanced stability, bioavailability, or specific biological activity.
• Chemical Biology Probes: Utilized in the development of molecular probes to study enzyme function and protein-protein interactions within biological systems.
• Material Science: Potential applications in the synthesis of functionalized polymers or surface-modifying agents due to its reactive thiol group.

Basic Information

Item	Details
Product Name	1-Pyrrolidinecarboxamide,3-Mercapto-,(S)-(9Ci)
CAS No.	129243-48-7
Molecular Formula	C5H10N2OS
Molecular Weight	146.21 g/mol
Synonyms	(S)-3-Mercaptopyrrolidine-1-carboxamide; (S)-3-Mercapto-1-pyrrolidinecarboxamide; L-3-Mercaptopyrrolidine-1-carboxamide; 3-Thiol-pyrrolidine-1-carboxamide, (S)-; 3-Mercapto-1-pyrrolidinecarboxamide, (S)-; 3-Sulfanyl-1-pyrrolidinecarboxamide, (S)-; (S)-3-Sulfanylpyrrolidine-1-carboxamide; (S)-3-Mercaptopyrrolidinecarboxamide
EINECS	Contact for details

Quality Control

Our 1-Pyrrolidinecarboxamide,3-Mercapto-,(S)-(9Ci) is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation, the container should be purged with inert gas after each opening to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.