Description

2-Aminomethyl-4-(4-Chlorophenyl)-4-Hydroxybutyric Acid is a specialized chiral intermediate of significant importance in the synthesis of high-value pharmaceutical compounds. Its unique structure, featuring both amino and hydroxy functional groups on a butyric acid backbone, makes it a critical building block for active pharmaceutical ingredients (APIs). This compound is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the research and production of novel central nervous system (CNS) drugs and other therapeutic APIs.
• Agrochemical Synthesis: Used as a precursor in the development of advanced pesticides and herbicides, leveraging its chlorophenyl moiety.
• Peptidomimetic Research: Serves as a constrained amino acid analog in the design of peptide-like molecules for drug discovery.
• Ligand and Catalyst Development: Utilized in organic chemistry for creating novel chiral ligands and catalysts for asymmetric synthesis.
• Academic and R&D: Employed in university and corporate research laboratories for methodological studies and the exploration of new chemical entities.

Basic Information

Product Name	2-Aminomethyl-4-(4-Chlorophenyl)-4-Hydroxybutyric Acid
CAS No.	129238-76-2
Molecular Formula	C11H14ClNO3
Molecular Weight	243.69 g/mol
Synonyms	4-(4-Chlorophenyl)-4-hydroxy-2-(aminomethyl)butanoic acid; (R/S)-2-Aminomethyl-4-(4-chlorophenyl)-4-hydroxybutyric acid; 4-Hydroxy-4-(4-chlorophenyl)-2-(aminomethyl)butyric acid; Gabapentin related compound C (chlorophenyl analog); ACHB; 4-(p-Chlorophenyl)-4-hydroxy-2-(aminomethyl)butyric acid
EINECS	Contact for details

Quality Control

Every batch of 2-Aminomethyl-4-(4-Chlorophenyl)-4-Hydroxybutyric Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for pharmaceutical R&D and synthesis. A Certificate of Analysis (COA) detailing purity, chiral purity (if applicable), and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.