Description

Ac-D-2-Nal-D-4-Clphe-D-3-Pal is a synthetic, non-natural peptide derivative designed for advanced research and development. This compound is a critical building block in the development of novel peptide-based pharmaceuticals and biochemical tools, offering high specificity and stability. It is primarily utilized by research institutions and pharmaceutical companies focused on oncology, metabolic disorders, and targeted drug delivery systems.

Application

• Pharmaceutical R&D: Serves as a key intermediate in the synthesis of peptide drug candidates targeting G-protein-coupled receptors (GPCRs).
• Biochemical Research: Used as a reference standard or a molecular probe in structure-activity relationship (SAR) studies and receptor binding assays.
• Peptide Library Synthesis: An essential component for constructing specialized peptide libraries for high-throughput screening in drug discovery.
• Academic Research: Employed in university and institutional labs for studying peptide conformation, stability, and bioactivity.
• Diagnostic Development: Potential use in the development of diagnostic assays and imaging agents due to its tailored structure.

Basic Information

Product Name	Ac-D-2-Nal-D-4-Clphe-D-3-Pal
CAS No.	129225-22-5
Molecular Formula	C32H31ClN4O5
Molecular Weight	587.06 g/mol
Synonyms	Ac-D-2-Naphthylalanine-D-4-Chlorophenylalanine-D-3-Pyridylalanine; N-Acetyl-D-2-Nal-D-4-Cl-Phe-D-Pal; Ac-D-Nal(2)-D-Phe(4-Cl)-D-Pal(3); 129225-22-5; N-Acetyl-D-2-naphthylalanyl-D-4-chlorophenylalanyl-D-3-(3-pyridyl)alanine; D-Peptide inhibitor analog; GPCR peptide modulator intermediate
EINECS	Contact for details

Quality Control

Our Ac-D-2-Nal-D-4-Clphe-D-3-Pal is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure stereochemical integrity. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.