Description

3-Pentanone, 4-Hydroxy-2,2-Dimethyl-, (S)- (9Ci) is a chiral, optically active ketone derivative that serves as a valuable building block in advanced organic synthesis. Its defined stereochemistry and functional groups make it a critical intermediate for producing high-value, enantiomerically pure compounds. This product is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific chiral centers into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing novel therapeutics.
• Agrochemical Synthesis: Used in the production of enantiomerically pure pesticides and herbicides, where specific stereochemistry can impact biological activity.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and other specialty chemicals requiring precise stereochemical control.
• Asymmetric Catalysis Research: Employed as a standard or substrate in academic and industrial research focused on developing new chiral catalysts and synthetic methodologies.
• Ligand and Auxiliary Synthesis: Utilized for constructing chiral ligands, auxiliaries, and resolving agents used in stereoselective transformations.

Basic Information

Product Name	3-Pentanone, 4-Hydroxy-2,2-Dimethyl-, (S)- (9Ci)
CAS No.	129215-75-4
Molecular Formula	C7H14O2
Molecular Weight	130.18 g/mol
Synonyms	(S)-4-Hydroxy-2,2-dimethyl-3-pentanone; (S)-4-Hydroxy-2,2-dimethylpentan-3-one; (S)-2,2-Dimethyl-4-hydroxypentan-3-one; (S)-3-Pentanone, 4-hydroxy-2,2-dimethyl-; (S)-4-Hydroxy-2,2-dimethyl-3-oxopentane; (S)-HDMP; (S)-Pantolactone related intermediate
EINECS	Contact for details

Quality Control

Our (S)-4-Hydroxy-2,2-dimethyl-3-pentanone is manufactured under strict quality management systems. Each batch is characterized and tested to ensure identity, purity, and enantiomeric excess meet stringent specifications. We provide comprehensive Certificates of Analysis (COA) detailing results for chiral purity (by chiral HPLC or GC), chemical assay, and specific impurity profiles. Our quality commitment supports applications requiring cGMP and ICH Q7 guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed when not in use to prevent evaporation and concentration changes. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.