Description

(R)-(+)-n-Isopropyl-1-Phenyl-2-(1-Piperidino)Ethylamine is a chiral amine building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of enantiomerically pure pharmaceuticals and fine chemicals, where stereochemical control is critical for efficacy and safety. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Asymmetric Synthesis Catalyst/ Ligand: Used in the preparation of chiral ligands for transition metal catalysts, enabling enantioselective transformations.
• Agrochemical Research: Employed as a building block for developing novel, enantiopure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Synthesis: A versatile intermediate for creating complex molecules with specific stereochemistry for material science and specialty applications.
• Academic & Industrial R&D: Utilized in methodological research for new synthetic routes and the study of structure-activity relationships (SAR).

Basic Information

Product Name	(R)-(+)-n-Isopropyl-1-Phenyl-2-(1-Piperidino)Ethylamine
CAS No.	129157-10-4
Molecular Formula	C16H26N2
Molecular Weight	246.40 g/mol
Synonyms	(R)-(+)-N-Isopropyl-1-phenyl-2-(1-piperidinyl)ethylamine; (R)-N-Isopropyl-1-phenyl-2-(piperidin-1-yl)ethan-1-amine; (R)-1-Phenyl-2-(1-piperidinyl)-1-(isopropylamino)ethane; (R)-Isopropylphenylpiperidinoethylamine; (R)-IPPEA; (R)-(+)-N-Isopropyl-N-(1-phenyl-2-piperidin-1-ylethyl)amine; (R)-1-(1-Phenylethyl)-2-(isopropylamino)piperidine (tautomeric form)
EINECS	Contact for details

Quality Control

Our (R)-(+)-n-Isopropyl-1-Phenyl-2-(1-Piperidino)Ethylamine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with customer specifications and high industry standards. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.