Description

4-(6-Methoxynaphthalen-2-Yl)-4-Oxo-2-Butenoic Acid is a high-purity, specialized organic compound with a defined molecular structure, serving as a critical advanced intermediate in pharmaceutical synthesis. Its value lies in its role as a key building block for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex naphthalene-based scaffolds. This product is essential for research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in the synthesis of new chemical entities and complex molecules.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of novel Active Pharmaceutical Ingredients (APIs), especially those with naphthalene-based structures.
• Research & Development: Used in medicinal chemistry for the discovery and optimization of new drug candidates, leveraging its reactive keto-acid functionality.
• Fine Chemical Synthesis: Serves as a precursor for synthesizing more complex organic molecules used in agrochemicals, dyes, and specialty materials.
• Academic Research: Employed in university and institutional labs for studying organic reaction mechanisms and developing new synthetic methodologies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	4-(6-Methoxynaphthalen-2-Yl)-4-Oxo-2-Butenoic Acid
CAS No.	129119-99-9
Molecular Formula	C15H12O4
Molecular Weight	256.25 g/mol
Synonyms	4-(6-Methoxy-2-naphthyl)-4-oxo-2-butenoic acid; 2-Butenoic acid, 4-(6-methoxy-2-naphthalenyl)-4-oxo-; 4-(6-Methoxynaphthalen-2-yl)-4-oxobut-2-enoic acid; (E)-4-(6-Methoxynaphthalen-2-yl)-4-oxobut-2-enoic acid; 4-Oxo-4-(6-methoxynaphthalen-2-yl)but-2-enoic acid; 129119-99-9; 4-(6-Methoxy-2-naphthoyl)acrylic acid
EINECS	Contact for details

Quality Control

Our 4-(6-Methoxynaphthalen-2-Yl)-4-Oxo-2-Butenoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting specifications for use as a pharmaceutical intermediate. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request, supporting regulatory submissions and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.