Description

4-Bromophenyl Trifluoromethanesulfonate is a versatile and high-purity triflate ester building block used extensively in advanced organic synthesis. Its primary value lies in its exceptional reactivity as an arylating agent, enabling efficient cross-coupling reactions to construct complex molecular architectures. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for Suzuki, Stille, and Negishi cross-coupling reactions to introduce the 4-bromophenyl moiety into drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific aryl ether or biaryl structures.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized phosphine ligands and organometallic catalysts.
• Material Science: Employed in the creation of monomers for high-performance polymers, liquid crystals, and organic electronic materials.
• Chemical Research: A valuable reagent for methodological development in palladium-catalyzed transformations and nucleophilic aromatic substitution.
• Fine Chemical Production: Integral to the multi-step synthesis of complex dyes, pigments, and other specialty chemicals.

Basic Information

Product Name	4-Bromophenyl Trifluoromethanesulfonate
CAS No.	129112-25-0
Molecular Formula	C7H4BrF3O3S
Molecular Weight	305.07 g/mol
Synonyms	4-Bromophenyl Triflate; 1-Bromo-4-(trifluoromethanesulfonyloxy)benzene; p-Bromophenyl Trifluoromethanesulfonate; Trifluoromethanesulfonic Acid 4-Bromophenyl Ester; 4-Bromophenyl Trifluoromethylsulfonate; (4-Bromophenyl) Triflate; 4-Bromo-1-(trifluoromethanesulfonyloxy)benzene
EINECS	Contact for details

Quality Control

Every batch of 4-Bromophenyl Trifluoromethanesulfonate is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency. Our standard grade typically meets a purity specification of ≥97% (by HPLC), suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.