Description

Methyl 4-Chloro-6-Oxo-1-[3-(Trifluoromethyl)Phenyl]-1,6-Dihydro-3-Pyridazinecarboxylate CAS NO 129109-18-8 is a high-value, multi-functional heterocyclic building block characterized by its pyridazine core and trifluoromethylphenyl substituent. This compound is essential for advanced research and development in medicinal chemistry, where it serves as a critical precursor for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers engaged in the development of new therapeutic agents and crop protection solutions.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of novel drug candidates, particularly in therapeutic areas targeting inflammation, oncology, and central nervous system (CNS) disorders.
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and insecticides, leveraging the biological activity of the pyridazine and trifluoromethyl motifs.
• Chemical Biology Probe Development: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways in academic and industrial research settings.
• Material Science Applications: Potential use as a monomer or additive in the synthesis of specialty polymers and advanced materials with specific electronic or surface properties.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis projects and scale-up activities for client-specific molecules.

Basic Information

Product Name	Methyl 4-Chloro-6-Oxo-1-[3-(Trifluoromethyl)Phenyl]-1,6-Dihydro-3-Pyridazinecarboxylate
CAS No.	129109-18-8
Molecular Formula	C13H8ClF3N2O3
Molecular Weight	332.66 g/mol
Synonyms	Methyl 4-chloro-6-oxo-1-[3-(trifluoromethyl)phenyl]-1,6-dihydropyridazine-3-carboxylate; 1,6-Dihydro-4-chloro-6-oxo-1-(3-trifluoromethylphenyl)-3-pyridazinecarboxylic Acid Methyl Ester; 4-Chloro-1-(3-trifluoromethylphenyl)-1,6-dihydro-6-oxo-3-pyridazinecarboxylic Acid Methyl Ester; Methyl 4-chloro-6-oxo-1-(3-trifluoromethylphenyl)-1H-pyridazine-3-carboxylate; 129109-18-8; 3-Pyridazinecarboxylic acid, 4-chloro-1,6-dihydro-6-oxo-1-[3-(trifluoromethyl)phenyl]-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 4-Chloro-6-Oxo-1-[3-(Trifluoromethyl)Phenyl]-1,6-Dihydro-3-Pyridazinecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider inert atmosphere conditions to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Maximum Impurity	≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.