Description

Phenylalanine,n-[(1,1-Dimethylethoxy)Carbonyl]-4-Fluoro- CAS NO 129101-25-3 is a protected amino acid derivative, specifically a Boc-protected 4-fluorophenylalanine analog, serving as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring high-purity, structurally defined intermediates for the development of novel peptides and bioactive molecules. It is primarily utilized in pharmaceutical R&D, agrochemical synthesis, and as a key precursor in the production of complex chemical entities where the introduction of a fluorine atom and specific stereochemistry is required.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of peptide-based drugs, protease inhibitors, and other active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate fluorinated phenylalanine residues, modifying peptide stability and bioactivity.
• Agrochemical Research: Serves as a precursor in the development of novel herbicides and pesticides with enhanced properties.
• Chemical Biology & Proteomics: Employed in the study of protein structure and function, and in the creation of activity-based probes.
• Material Science: Potential monomer for creating specialized polymers and advanced materials with unique characteristics.
• Academic & Industrial R&D: Fundamental reagent for methodological development in organic chemistry and medicinal chemistry programs.

Basic Information

Item	Detail
Product Name	Phenylalanine,n-[(1,1-Dimethylethoxy)Carbonyl]-4-Fluoro-
CAS No.	129101-25-3
Molecular Formula	C14H18FNO4
Molecular Weight	283.30 g/mol
Synonyms	Boc-4-Fluoro-DL-phenylalanine; N-(tert-Butoxycarbonyl)-4-fluoro-DL-phenylalanine; 4-Fluoro-DL-phenylalanine N-Boc derivative; (RS)-2-[(tert-Butoxycarbonyl)amino]-3-(4-fluorophenyl)propanoic acid; Boc-Phe(4-F)-OH; N-Boc-4-fluorophenylalanine; tert-Butyl (4-fluorophenylalanyl)carbamate; DL-4-Fluorophenylalanine N-Boc
EINECS	Contact for details

Quality Control

Our Phenylalanine,n-[(1,1-Dimethoxyethoxy)Carbonyl]-4-Fluoro- is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via IR and NMR spectroscopy. We provide Certificates of Analysis (COA) with every shipment, detailing all critical parameters to ensure the material meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	DL-Mixture (Racemic)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.