Description

3'-Deoxy-3'-Fluoro-N6-Benzoyladenosine is a chemically modified nucleoside analog, specifically engineered for advanced research and development applications. This compound is a critical intermediate in the synthesis of novel pharmaceutical agents, particularly in the development of antiviral and anticancer therapeutics. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on nucleotide-based drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of modified nucleoside analogs for antiviral and anticancer drug candidates.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate RNA polymerase and other nucleotide-processing enzymes.
• Pro-drug Development: Serves as a protected precursor molecule for the development of nucleotide pro-drugs with enhanced cellular uptake and metabolic stability.
• Antiviral Agent Synthesis: A crucial intermediate in the research and development pipeline for novel antiviral medications targeting viral replication.
• Labeled Compound Synthesis: Can be used as a starting point for synthesizing isotopically labeled (e.g., 13C, 15N) compounds for metabolic tracing and pharmacokinetic studies.
• Academic Research: Employed in university and institutional labs for studying structure-activity relationships (SAR) of nucleoside derivatives.

Basic Information

Product Name	3'-Deoxy-3'-Fluoro-N6-Benzoyladenosine
CAS No.	129054-67-7
Molecular Formula	C17H16FN5O4
Molecular Weight	373.34 g/mol
Synonyms	3'-Deoxy-3'-fluoroadenosine N6-benzoyl derivative; 3'-Fluoro-3'-deoxy-N6-benzoyladenosine; 9-[(2R,3R,4S,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-N-phenyl-9H-purin-6-amine; 3'-F-3'-dA(Bz); N6-Benzoyl-3'-deoxy-3'-fluoroadenosine; 3'-Fluoro-3'-deoxyadenosine N6-benzoate
EINECS	Contact for details

Quality Control

Our 3'-Deoxy-3'-Fluoro-N6-Benzoyladenosine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable for the production of pharmaceutical intermediates, ensuring traceability and documentation for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.