Description

R-6-Fluorochromane-2-Carboxaldehyde is a high-value fluorinated organic building block characterized by its chromane scaffold and aldehyde functionality. This compound is essential for advanced organic synthesis, particularly in the development of complex molecules where its unique structure imparts specific electronic and steric properties. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for use in medicinal chemistry and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated chromane structure.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, or organic electronic materials due to its rigid, aromatic core.
• Chemical Biology Probes: Utilized in the synthesis of fluorescent tags or molecular probes for studying biological processes.
• Catalyst & Ligand Development: Acts as a starting material for synthesizing novel chiral ligands or organocatalysts for asymmetric synthesis.
• Flavor & Fragrance Chemistry: Potential intermediate for creating complex aroma chemicals with unique olfactory profiles.

Basic Information

Product Name	R-6-Fluorochromane-2-Carboxaldehyde
CAS No.	129050-22-2
Molecular Formula	C10H9FO2
Molecular Weight	180.18 g/mol
Synonyms	6-Fluorochroman-2-carboxaldehyde; (R)-6-Fluorochromane-2-carbaldehyde; (2R)-6-Fluoro-3,4-dihydro-2H-1-benzopyran-2-carboxaldehyde; 6-Fluoro-2-chromancarboxaldehyde; (R)-6-Fluorochroman-2-carboxaldehyde; 129050-22-2; 6-Fluorochromane-2-carbaldehyde
EINECS	Contact for details

Quality Control

Our R-6-Fluorochromane-2-Carboxaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.