Description

11-Methoxy-16-Fluoroestradiol is a synthetic, fluorinated derivative of estradiol, a key steroid hormone. This compound is of significant interest in pharmaceutical research and development due to its modified structure, which can impart unique biological activity and metabolic stability. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, diagnostic tools, and in advanced biochemical studies.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel steroid-based therapeutics.
• Biochemical Research: Used as a reference standard or probe in studies investigating estrogen receptor binding affinity and selectivity.
• Drug Discovery: Employed in high-throughput screening and structure-activity relationship (SAR) studies for oncology and endocrinology targets.
• Diagnostic Agent Development: Potential use in the development of radiolabeled tracers for positron emission tomography (PET) imaging.
• Metabolic Studies: Acts as a substrate to study the effects of fluorination and methoxylation on steroid metabolism and pharmacokinetics.

Basic Information

Item	Detail
Product Name	11-Methoxy-16-Fluoroestradiol
CAS No.	129000-37-9
Molecular Formula	C19H25FO3
Molecular Weight	320.40 g/mol
Synonyms	16-Fluoro-11-methoxyestra-1,3,5(10)-triene-3,17β-diol; 11-Methoxy-16α-fluoroestradiol; 16-Fluoro-11-methoxyestradiol; 16-Fluoro-11-methoxy-oestradiol; Estra-1,3,5(10)-triene-3,17-diol, 16-fluoro-11-methoxy-, (16α,17β)-; 16α-Fluoro-11β-methoxyestradiol
EINECS	Contact for details

Quality Control

Our 11-Methoxy-16-Fluoroestradiol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements of research and development applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.