Description

Siloxanes And Silicones, (2S-Trans)-(4-Hydroxy-2-Pyrrolidinyl)Carbonyloxy Me, Hydroxy-Terminated is a specialized organosilicon compound featuring a chiral pyrrolidine-derived moiety and reactive hydroxy end groups. This unique molecular architecture provides a versatile platform for synthesizing advanced silicone polymers and copolymers with tailored properties. It is a critical intermediate for manufacturers in the pharmaceutical, advanced materials, and personal care industries seeking to incorporate functional siloxane units into high-performance products.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) or prodrugs that leverage the biocompatibility and pharmacokinetic modulation of siloxane structures.
• Specialty Silicone Synthesis: Serves as a functional monomer or chain extender for creating hydroxy-terminated polydimethylsiloxanes (PDMS) and other silicone copolymers with precise molecular weights and architectures.
• Bioconjugation & Drug Delivery: Used to create silicone-based linkers or carriers for targeted drug delivery systems, taking advantage of its reactive termini for attaching therapeutic payloads.
• Advanced Material Modifier: Imparts specific surface properties, flexibility, or compatibility when incorporated into coatings, adhesives, sealants, and elastomers (CASE).
• Cosmetic & Personal Care Ingredients: Intermediate for producing novel silicone derivatives that offer unique sensory profiles, emolliency, or film-forming properties in formulations.
• Chiral Catalyst/ Ligand Support: The chiral center allows its use in constructing immobilized catalysts or ligands for asymmetric synthesis.

Basic Information

Product Name	Siloxanes And Silicones, (2S-Trans)-(4-Hydroxy-2-Pyrrolidinyl)Carbonyloxy Me, Hydroxy-Terminated
CAS No.	128973-74-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(2S-trans)-4-Hydroxy-2-pyrrolidinecarboxylic acid methyl ester, siloxanes and silicones, hydroxy-terminated; Hydroxy-terminated (2S-trans)-(4-hydroxy-2-pyrrolidinyl)carbonyloxy methyl siloxane; Siloxane, hydroxy-terminated, (2S-trans)-(4-hydroxy-2-pyrrolidinyl)carbonyloxy methyl; Methyl (2S,4R)-4-hydroxy-2-pyrrolidinecarboxylate siloxane derivative; Hydroxy-terminated pyrrolidine-functional siloxane; CAS 128973-74-0
EINECS	Contact for details

Quality Control

Our production of Siloxanes And Silicones, (2S-Trans)-(4-Hydroxy-2-Pyrrolidinyl)Carbonyloxy Me, Hydroxy-Terminated adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, NMR for structural confirmation, and titration for hydroxy value determination, to ensure it meets precise customer specifications. Certificates of Analysis (COA) documenting all critical parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is sensitive to strong alkali and organic solvents; keep away from incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Chiral Purity	≥ 98.0% ee
Hydroxy Value	As per customer requirement
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.