Description

[1-(4-Phenoxybut-2-Ynyl)-4-Phenyl-4-Piperidyl] Propanoate Hydrochlorid E is a specialized pharmaceutical intermediate and research chemical. This compound is of significant interest for its potential role in the development of novel therapeutic agents targeting the central nervous system. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in advanced medicinal chemistry and drug discovery programs. The material is supplied as a high-purity chemical entity to support rigorous development and analytical work.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential new chemical entities (NCEs) for drug discovery.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize pharmacological profiles.
• Neuroscience Research: Investigated for activity in preclinical models related to neurological and psychiatric disorders.
• Reference Standard: Serves as an analytical standard for quality control and method development in API manufacturing.
• Process Development: Employed in the scale-up and optimization of synthetic routes for advanced pharmaceutical ingredients.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and pharmacology.

Basic Information

Product Name	[1-(4-Phenoxybut-2-Ynyl)-4-Phenyl-4-Piperidyl] Propanoate Hydrochlorid E
CAS No.	128864-80-2
Molecular Formula	C24H27NO3·HCl
Molecular Weight	429.94 g/mol
Synonyms	1-(4-Phenoxy-2-butynyl)-4-phenyl-4-piperidinol propionate hydrochloride; 4-Phenyl-1-[4-(phenoxy)-2-butynyl]-4-piperidinyl propionate hydrochloride; Propanoic acid, 4-phenyl-1-[4-(phenoxy)-2-butynyl]-4-piperidinyl ester, hydrochloride; 4-Phenyl-1-(4-phenoxybut-2-yn-1-yl)piperidin-4-yl propionate hydrochloride; L-687,384 hydrochloride; L687384 hydrochloride
EINECS	Contact for details

Quality Control

Our [1-(4-Phenoxybut-2-Ynyl)-4-Phenyl-4-Piperidyl] Propanoate Hydrochlorid E is manufactured under controlled conditions to ensure high chemical purity and batch-to-batch consistency, suitable for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to stringent internal quality standards and can support customer audits and regulatory documentation as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.