Description

2H-Pyrido(3,4-B)Indole-2-Ethanol, 1,3,4,9-Tetrahydro-α-(((1,1-Dime Thylethyl)Amino)Methyl-1-Methyl-, Dihydrochloride is a high-purity, complex heterocyclic compound supplied as a dihydrochloride salt. This product is a critical advanced pharmaceutical intermediate, valued for its role in the synthesis of novel therapeutic agents targeting central nervous system disorders. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of next-generation neuropharmacological treatments.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of experimental neuroactive compounds and receptor modulators.
• Neurological Research: Used in academic and industrial R&D for studying neurological pathways and developing potential treatments for CNS disorders.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Reference Standard: Employed as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.
• Preclinical Development: Utilized in the production of materials for toxicology, pharmacokinetics, and early-stage animal studies.

Basic Information

Product Name	2H-Pyrido(3,4-B)Indole-2-Ethanol, 1,3,4,9-Tetrahydro-α-(((1,1-Dime Thylethyl)Amino)Methyl-1-Methyl-, Dihydrochloride
CAS No.	128857-34-1
Molecular Formula	C19H29N3O • 2HCl
Molecular Weight	388.37 g/mol (free base)
Synonyms	1,3,4,9-Tetrahydro-α-[[(1,1-dimethylethyl)amino]methyl]-1-methyl-2H-pyrido[3,4-b]indole-2-ethanol dihydrochloride; Tetrahydroharmine derivative dihydrochloride; 2-(1,3,4,9-Tetrahydro-1-methyl-2H-pyrido[3,4-b]indol-2-yl)-1-[(tert-butylamino)methyl]ethanol dihydrochloride; TB-2 Dihydrochloride; Norharmane derivative; β-Carboline derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 2H-Pyrido(3,4-B)Indole-2-Ethanol, 1,3,4,9-Tetrahydro-α-(((1,1-Dime Thylethyl)Amino)Methyl-1-Methyl-, Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.2%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.