Description

2-(Nitrooxy)Ethyl Apovincaminate is a specialized organic compound of significant interest in advanced pharmaceutical research and development. This molecule is valued for its potential as a key synthetic intermediate or active pharmaceutical ingredient (API) in the creation of novel therapeutic agents. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of next-generation medications, particularly those targeting neurological and cardiovascular systems. The compound's unique structure combines functional groups that are critical for specific biological activity and pharmacokinetic properties.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of complex drug candidates, particularly vinca alkaloid derivatives.
• Neurological Research: Investigated for potential applications in the development of agents targeting cognitive function and cerebral blood flow.
• Vasodilatory Agent Development: Used in R&D for compounds intended to improve peripheral and cerebral circulation.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Preclinical Studies: Utilized in animal model research to establish pharmacokinetic and pharmacodynamic profiles.
• Process Chemistry: Acts as a starting material or intermediate in optimizing scalable synthetic routes for API manufacturing.

Basic Information

Product Name	2-(Nitrooxy)Ethyl Apovincaminate
CAS No.	128759-76-2
Molecular Formula	C24H29N3O6
Molecular Weight	455.51 g/mol
Synonyms	Apovincaminic Acid 2-(Nitrooxy)ethyl Ester; Ethyl 2-(Nitrooxy)ethyl Apovincaminate; Vinpocetine Nitrate Ester Derivative; 2-Nitrooxyethyl Apovincaminate; (3α,16α)-Eburnamenine-14-carboxylic Acid 2-(Nitrooxy)ethyl Ester; VINP Nitrate Analog; CAS 128759-76-2
EINECS	Contact for details

Quality Control

Our 2-(Nitrooxy)Ethyl Apovincaminate is produced under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all relevant specifications. Our commitment to cGMP principles and regulatory compliance ensures traceability and consistency for our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 0.5%
Assay	97.0% - 102.0% (on dried basis)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.