Description

7-[(1S,2R,3R,4R)-3-[(1E,3R)-3-Hydroxy-4-(4-Iodophenoxy)-1-Butenyl]-7-Oxabicyclo[2.2.1]Hept-2-Yl]-5Z-Heptenoic Acid is a high-purity, synthetically derived prostaglandin analog with a complex, stereospecific structure. This compound is valued for its potent and selective biological activity, making it a critical advanced pharmaceutical intermediate in the development of novel therapeutics. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in drug discovery and development, particularly for programs targeting inflammation, cardiovascular function, and ocular diseases.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potent prostaglandin-based active pharmaceutical ingredients (APIs).
• Biomedical Research: Used as a reference standard and a tool compound in pharmacological studies to investigate prostaglandin receptor pathways and signaling mechanisms.
• Drug Discovery: Employed in high-throughput screening and lead optimization for developing new anti-inflammatory and vasoactive agents.
• Ophthalmic Drug Development: Investigated for potential use in the formulation of treatments for glaucoma and other intraocular pressure-related conditions.
• Chemical Synthesis: Utilized in advanced organic synthesis for the preparation of other complex, stereochemically defined molecules.

Basic Information

Product Name	7-[(1S,2R,3R,4R)-3-[(1E,3R)-3-Hydroxy-4-(4-Iodophenoxy)-1-Butenyl]-7-Oxabicyclo[2.2.1]Hept-2-Yl]-5Z-Heptenoic Acid
CAS No.	128719-90-4
Molecular Formula	C24H29IO5
Molecular Weight	524.39 g/mol
Synonyms	17-Phenyl trinor Prostaglandin F2α Iodophenoxy Analogue; 7-[(1S,2R,3R,4R)-3-[(1E,3R)-3-Hydroxy-4-(4-Iodophenoxy)-1-buten-1-yl]-7-oxabicyclo[2.2.1]hept-2-yl]-5Z-heptenoic Acid; 4-(4-Iodophenoxy)-17-phenyl-trinor-PGF2α; Prostaglandin F2α analogue (4-iodophenoxy); AL-8810 (research code); 11-Deoxy-16-(4-iodophenoxy)-17,18,19,20-tetranor-PGF2α
EINECS	Contact for details

Quality Control

This product is manufactured under strict cGMP (current Good Manufacturing Practice) guidelines to ensure batch-to-batch consistency and traceability. Quality is verified through a comprehensive suite of analytical methods including HPLC, NMR, and Mass Spectrometry to confirm identity, purity, and stereochemical integrity. A detailed Certificate of Analysis (COA) is provided with each batch, documenting compliance with stringent in-house specifications developed for pharmaceutical research applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.