Description

Boc-Hoarg-Oh CAS NO 128719-65-3 is a protected amino acid derivative, specifically the N-Boc derivative of L-homoarginine, serving as a critical building block in advanced peptide synthesis. Its primary value lies in providing a protected guanidino group, which is essential for constructing peptides containing arginine or homoarginine residues without unwanted side reactions during coupling. This high-purity intermediate is indispensable for researchers and manufacturers in pharmaceutical development, particularly for creating novel therapeutic peptides, and for use in biochemical research applications.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected intermediate for the controlled incorporation of homoarginine into peptide chains.
• Pharmaceutical R&D: Building block for the development of peptide-based drugs, hormone analogs, and enzyme inhibitors.
• Bioconjugation: Used to introduce a protected guanidine functionality into biomolecules for labeling or cross-linking studies.
• Chemical Biology Probes: Synthesis of labeled or modified peptides used to study protein-protein interactions and enzyme mechanisms.
• Process Development: Serves as a starting material or intermediate in the scalable synthesis of complex peptide Active Pharmaceutical Ingredients (APIs).
• Academic Research: Fundamental studies in peptide chemistry and the synthesis of reference standards.

Basic Information

Item	Details
Product Name	Boc-Hoarg-Oh
CAS No.	128719-65-3
Molecular Formula	C₁₂H₂₄N₄O₄
Molecular Weight	288.34 g/mol
Synonyms	N-α-Boc-L-homoarginine; Boc-L-homoarginine; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-((tert-butoxycarbonyl)amino)hexanoic acid; Boc-Homoarg-OH; Fmoc-Homoarg(Boc)-OH (related); NG-Boc-L-homoarginine; tert-Butyloxycarbonyl-L-homoarginine; Boc-HArg-OH
EINECS	Contact for details

Quality Control

Our Boc-Hoarg-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemicals and can provide material suitable for cGMP manufacturing upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥98.0%
Optical Rotation [α]²⁰D	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.