Description

2H-Pyran-4-Carboxaldehyde, Tetrahydro-2-Methyl-6-Oxo-, cis- (9Ci) is a specialized heterocyclic aldehyde building block of significant interest in advanced organic synthesis. This compound matters for its role as a key chiral intermediate, enabling the construction of complex molecular architectures with precise stereochemistry. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly in classes requiring fused pyran or lactone ring systems.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where its aldehyde functionality allows for further derivatization.
• Flavor & Fragrance Chemistry: Serves as a precursor for creating complex, oxygenated aroma compounds and specialty flavors.
• Material Science: Employed in the research of specialty polymers and advanced organic materials that incorporate heterocyclic motifs.
• Academic & Contract Research: A valuable reagent for methodological studies in asymmetric synthesis and total synthesis projects.

Basic Information

Product Name	2H-Pyran-4-Carboxaldehyde, Tetrahydro-2-Methyl-6-Oxo-, cis- (9Ci)
CAS No.	128683-38-5
Molecular Formula	C7H10O3
Molecular Weight	142.15 g/mol
Synonyms	cis-2-Methyl-6-oxotetrahydro-2H-pyran-4-carbaldehyde; (4S,6R)-6-Methyl-4,5,6,7-tetrahydro-2H-pyran-4-carboxaldehyde; Tetrahydro-2-methyl-6-oxo-2H-pyran-4-carboxaldehyde, cis-; 4-Formyl-2-methyl-5,6-dihydro-2H-pyran-6-one; 2-Methyl-6-oxo-tetrahydro-2H-pyran-4-carboxaldehyde; 4-Carboxaldehyde-2-methyl-5,6-dihydro-2H-pyran-6-one; 128683-38-5
EINECS	Contact for details

Quality Control

Every batch of 2H-Pyran-4-Carboxaldehyde, Tetrahydro-2-Methyl-6-Oxo-, cis- (9Ci) undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality commitment includes adherence to cGMP principles for pharmaceutical-grade material. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, well-ventilated area. This material is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.