Description

6-Iodochroman-2-One is a versatile iodinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce iodine functionality into chroman-based scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or possessing anti-inflammatory activity.
• Agrochemical Research: Used in the development of novel active ingredients for crop protection, where the chroman and iodine moieties can contribute to unique biological activity.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Precursor: Employed in the synthesis of organic electronic materials and advanced polymers where the chroman structure imparts specific photophysical properties.
• Chemical Biology Probe Synthesis: Utilized to build molecular probes for studying enzyme function and biological pathways, leveraging iodine for potential further functionalization or as a spectroscopic label.
• Academic & Institutional Research: A valuable reagent for methodological studies in organic chemistry, particularly in cross-coupling reactions and heterocyclic chemistry.

Basic Information

Product Name	6-Iodochroman-2-One
CAS No.	128651-99-0
Molecular Formula	C9H7IO2
Molecular Weight	274.06 g/mol
Synonyms	6-Iodochroman-2-one; 2H-1-Benzopyran-2-one, 6-iodo-3,4-dihydro-; 6-Iodo-3,4-dihydro-2H-chromen-2-one; 6-Iodo-3,4-dihydrocoumarin; 6-Iododihydrocoumarin; 3,4-Dihydro-6-iodo-2H-1-benzopyran-2-one
EINECS	Contact for details

Quality Control

Our 6-Iodochroman-2-One is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and reliability for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to minimize exposure to moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.