Description

L-Allothreonine, n-[(1,1-Dimethylethoxy)Carbonyl]-o-(Phenylmethyl)- is a protected derivative of the non-proteinogenic amino acid allothreonine, featuring Boc (tert-butoxycarbonyl) and benzyl protecting groups. This compound is a critical chiral building block in organic synthesis, valued for its role in constructing complex peptide chains and other bioactive molecules with precise stereochemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, peptide-based drugs, and advanced biochemical research.

Application

• Peptide Synthesis: A key chiral intermediate for the solid-phase and solution-phase synthesis of complex peptides and peptidomimetics.
• Pharmaceutical Research: Used in the research and development of new active pharmaceutical ingredients (APIs), especially those requiring specific stereochemical configurations.
• Bioconjugation & Probe Development: Serves as a building block for creating labeled peptides, affinity probes, and other tools for biochemical studies.
• Chemical Biology: Employed in the synthesis of custom amino acid analogs to study protein structure, function, and interactions.
• Agrochemical Research: Potential intermediate in the synthesis of specialized amino acid-based compounds for crop protection research.

Basic Information

Product Name	L-Allothreonine, n-[(1,1-Dimethylethoxy)Carbonyl]-o-(Phenylmethyl)-
CAS No.	128609-40-5
Molecular Formula	C16H23NO5
Molecular Weight	309.36 g/mol
Synonyms	Boc-L-allothreonine(Bzl)-OH; (2S,3S)-2-[(tert-Butoxycarbonyl)amino]-3-(benzyloxy)butanoic acid; N-Boc-O-benzyl-L-allothreonine; tert-Butyl ((2S,3S)-3-(benzyloxy)-1-hydroxy-1-oxobutan-2-yl)carbamate; L-allo-Threonine, N-Boc-O-Bzl; Boc-Thr(Bzl)-OH (alloisomer); N-(tert-Butoxycarbonyl)-O-benzyl-L-allothreonine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material that meets high-purity specifications suitable for research and pharmaceutical applications. Certificates of Analysis (COA) detailing identity, purity (by HPLC), and specific impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.