Description

2-Methyl-D-Tyrosine is a non-natural, chiral amino acid derivative of tyrosine, distinguished by a methyl group at the 2-position of the aromatic ring and the D-configuration. This specific stereochemistry and substitution pattern make it a valuable chiral building block and intermediate in advanced organic synthesis. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of peptide-based therapeutics, enzyme inhibitors, and novel diagnostic agents. The compound's structural features allow for the modulation of peptide conformation and biological activity.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel peptide drugs and enzyme inhibitors.
• Peptide Synthesis: Used as a modified amino acid residue to introduce steric and electronic effects, altering peptide stability and receptor binding.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies to investigate tyrosine metabolism and related pathways.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in the synthesis of complex, optically active molecules.
• Diagnostic Agent Development: Potential precursor for radiolabeled compounds used in Positron Emission Tomography (PET) imaging.

Basic Information

Product Name	2-Methyl-D-Tyrosine
CAS No.	128573-13-7
Molecular Formula	C10H13NO3
Molecular Weight	195.22 g/mol
Synonyms	D-2-Methyltyrosine; (R)-2-Amino-3-(2-methyl-4-hydroxyphenyl)propanoic acid; (R)-2-Methyltyrosine; H-D-2-Methyl-Tyr-OH; 2-Methyl-D-tyrosine; D-α-Methyltyrosine; D-2-Me-Tyr
EINECS	Contact for details

Quality Control

Our 2-Methyl-D-Tyrosine is manufactured under controlled conditions to ensure high chemical and chiral purity. Each batch undergoes rigorous analytical testing, including HPLC for assay and enantiomeric purity, IR and NMR for structural confirmation, and tests for residual solvents and moisture. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality system supports compliance with cGMP standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (HPLC)	≥99.0% (D-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.