Description

16β-(Acetyloxy)-3β-[[4-o-[6-o-(β-D-Glucopyranosyl)-β-D-Glucopyranosyl]-6-Deoxy-3-o-Methyl-β-D-Glucopyranosyl]Oxy]-14-Hydroxy-5β-Card-20(22)-Enolide is a high-purity, complex cardiac glycoside derivative used as a critical reference standard and active pharmaceutical ingredient (API) intermediate in advanced pharmaceutical research and development. This compound is essential for ensuring analytical accuracy and quality control in the production of specialized cardiovascular therapeutics. It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and academic institutions engaged in the synthesis and study of novel cardiotonic agents.

Application

• Pharmaceutical Reference Standard: Serves as a primary chemical reference material (CRM) for the qualitative and quantitative analysis of cardiac glycoside-based drugs using HPLC, LC-MS, and NMR.
• Active Pharmaceutical Ingredient (API) Intermediate: A key synthetic building block in the multi-step production of novel or generic cardiovascular medications.
• Biochemical Research: Used in pharmacological studies to investigate mechanisms of action related to sodium-potassium ATPase inhibition and cardiac contractility.
• Quality Control & Assurance: Employed in in-house laboratory testing to validate analytical methods and ensure batch-to-batch consistency of final drug products.
• Metabolite Studies: Utilized as a precursor or standard in the research of drug metabolism and pharmacokinetics (DMPK) for related therapeutic compounds.

Basic Information

Product Name	16β-(Acetyloxy)-3β-[[4-o-[6-o-(β-D-Glucopyranosyl)-β-D-Glucopyranosyl]-6-Deoxy-3-o-Methyl-β-D-Glucopyranosyl]Oxy]-14-Hydroxy-5β-Card-20(22)-Enolide
CAS No.	128533-42-6
Molecular Formula	C48H74O21
Molecular Weight	963.10 g/mol
Synonyms	16β-Acetoxy-3β-[(O-β-D-glucopyranosyl-(1→6)-O-β-D-glucopyranosyl-(1→4)-6-deoxy-3-O-methyl-β-D-glucopyranosyl)oxy]-14-hydroxy-5β-card-20(22)-enolide; 3β-[(O-β-D-Glucopyranosyl-(1→6)-O-β-D-glucopyranosyl-(1→4)-6-deoxy-3-O-methyl-β-D-glucopyranosyl)oxy]-16β-acetoxy-14-hydroxy-5β-card-20(22)-enolide; Desglucouzarin; A derivative of Uzarigenin; Cardiac glycoside trisaccharide derivative
EINECS	Contact for details

Quality Control

Our 16β-(Acetyloxy)-3β-[[4-o-[6-o-(β-D-Glucopyranosyl)-β-D-Glucopyranosyl]-6-Deoxy-3-o-Methyl-β-D-Glucopyranosyl]Oxy]-14-Hydroxy-5β-Card-20(22)-Enolide is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC purity assay, identity confirmation (IR, NMR), and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.