Description

1-(2,3-Dideoxy-2,3-Difluoroarabinofuranosyl)Cytosine is a fluorinated nucleoside analog, a key intermediate in the synthesis of novel antiviral and anticancer agents. Its modified sugar moiety confers unique biochemical properties, making it a valuable building block for pharmaceutical research and development. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and synthesis of nucleoside-based therapeutics targeting viral infections and oncology.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of experimental antiviral drugs, particularly those targeting DNA viruses.
• Anticancer Agent Research: Serves as a building block for developing novel nucleoside analogs that inhibit tumor cell proliferation.
• Biochemical Research: Used in studies investigating enzyme-substrate interactions, DNA/RNA synthesis inhibition, and metabolic pathways.
• Prodrug Development: Employed in the design and synthesis of prodrugs to enhance bioavailability and targeting of active pharmaceutical ingredients.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.

Basic Information

Product Name	1-(2,3-Dideoxy-2,3-Difluoroarabinofuranosyl)Cytosine
CAS No.	128496-20-8
Molecular Formula	C9H11F2N3O4
Molecular Weight	263.20 g/mol
Synonyms	2',3'-Dideoxy-2',3'-difluoroarabinofuranosylcytosine; 2',3'-Dideoxy-2',3'-difluoro-β-D-arabinofuranosylcytosine; 1-((2R,3R,4S,5R)-3,4-Difluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; DDFAC; 2',3'-Difluoro-2',3'-dideoxyarabinofuranosylcytosine
EINECS	Contact for details

Quality Control

Our 1-(2,3-Dideoxy-2,3-Difluoroarabinofuranosyl)Cytosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical research. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.