Description

Cyclopenta[B]Pyrrol-1(2H)-Amine, Hexahydro-2-(Methoxymethyl)-, (2S,3As,6As)- (9Ci) is a high-purity, stereochemically defined chiral amine building block of significant interest in advanced organic synthesis. Its value lies in its complex, fused bicyclic pyrrolidine structure, which serves as a critical scaffold for constructing pharmacologically active molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly where specific stereochemistry is required for biological activity. CAS No. 128495-97-6.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, especially in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective pesticides and herbicides where the specific spatial orientation of the molecule influences biological efficacy.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing novel chiral ligands and organocatalysts used in enantioselective transformations.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic and natural product synthesis.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals beyond life sciences.

Basic Information

Item	Details
Product Name	Cyclopenta[B]Pyrrol-1(2H)-Amine, Hexahydro-2-(Methoxymethyl)-, (2S,3As,6As)- (9Ci)
CAS No.	128495-97-6
Molecular Formula	C9H17NO
Molecular Weight	155.24 g/mol
Synonyms	(2S,3aS,6aS)-Hexahydro-2-(methoxymethyl)cyclopenta[b]pyrrol-1(2H)-amine; (2S,3aS,6aS)-2-(Methoxymethyl)octahydrocyclopenta[b]pyrrol-1-amine; Hexahydro-2-(methoxymethyl)-, (2S,3aS,6aS)-Cyclopenta[b]pyrrol-1(2H)-amine; Chiral Fused Bicyclic Pyrrolidine Amine; (2S,3aS,6aS)-1-Amino-2-(methoxymethyl)octahydrocyclopenta[b]pyrrole
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality control protocols to ensure batch-to-batch consistency and high chiral purity, which is critical for downstream synthesis. Quality is verified through a combination of chromatographic and spectroscopic methods, including HPLC for chiral purity and NMR for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profile is provided with each shipment to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended long-term storage at 2-8°C to maintain stability and prevent degradation. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.