Description

(1S,3R,5R,7S)-3-(1-Aminoethyl)Adamantan-1-Ol Hydrochloride is a high-purity, chiral adamantane derivative that serves as a critical advanced pharmaceutical intermediate. Its value lies in its rigid, three-dimensional adamantane scaffold, which is prized for enhancing the metabolic stability and bioavailability of drug candidates. This compound is essential for research and development chemists in the pharmaceutical industry, particularly for synthesizing novel antiviral and central nervous system (CNS) active agents.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel antiviral medications and treatments for neurological disorders.
• Protease Inhibitor Development: Used in research for creating inhibitors targeting specific viral proteases.
• Neurological Drug Research: Employed in the development of potential therapeutics for conditions like Alzheimer's and Parkinson's disease due to the blood-brain barrier permeability conferred by the adamantane group.
• Chemical Biology & Proteomics: Serves as a scaffold or tag in the design of chemical probes for studying enzyme function and protein interactions.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or precursor in stereoselective synthesis to create enantiomerically pure compounds.
• Material Science Research: Investigated as a monomer or additive for creating novel polymers with enhanced thermal and chemical stability.

Basic Information

Product Name	(1S,3R,5R,7S)-3-(1-Aminoethyl)Adamantan-1-Ol Hydrochloride
CAS No.	128487-57-0
Molecular Formula	C₁₂H₂₂ClNO
Molecular Weight	231.76 g/mol
Synonyms	(1S,3R,5R,7S)-3-(1-Aminoethyl)-1-adamantanol hydrochloride; (1S,3R,5R,7S)-3-(1-Aminoethyl)tricyclo[3.3.1.1³,⁷]decan-1-ol hydrochloride; 1-Aminoethyladamantanol HCl; 3-(1-Aminoethyl)-1-adamantanol hydrochloride (specified stereoisomer); 1-(1-Aminoethyl)adamantan-3-ol hydrochloride; Adamantane ethanolamine derivative hydrochloride; Chiral amino adamantanol hydrochloride
EINECS	Contact for details

Quality Control

Our (1S,3R,5R,7S)-3-(1-Aminoethyl)Adamantan-1-Ol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.