Description

3-(2-Chloro-4-Fluorophenyl)-1-Propene is a versatile halogenated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. Industries requiring high-purity intermediates for research, process development, and commercial manufacturing will find this product essential for constructing active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the biological activity of the fluorophenyl moiety.
• Liquid Crystal & OLED Materials: Serves as a building block for creating specialized aromatic cores used in electronic display technologies and organic light-emitting diodes.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries.
• Functional Material Precursor: Used in the synthesis of ligands for catalysts and monomers for high-performance polymers.

Basic Information

Product Name	3-(2-Chloro-4-Fluorophenyl)-1-Propene
CAS No.	128426-47-1
Molecular Formula	C9H8ClF
Molecular Weight	170.61 g/mol
Synonyms	2-Chloro-4-fluorocinnamyl chloride (common misnomer); 1-(2-Chloro-4-fluorophenyl)-2-propene; 3-(2-Chloro-4-fluorophenyl)prop-1-ene; (2-Chloro-4-fluorophenyl)allyl; 2-Chloro-4-fluoro-β-methylstyrene; Allyl-2-chloro-4-fluorobenzene; 128426-47-1
EINECS	Contact for details

Quality Control

Our 3-(2-Chloro-4-Fluorophenyl)-1-Propene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.