Description

(3-Bromo-1-Methylpropyl)Carbamic Acid tert-Butyl Ester is a high-purity, protected amino acid derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in peptide mimetics and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly for protease inhibitors and other biologically active molecules.
• Peptidomimetic Chemistry: Used to introduce the (3-bromo-1-methylpropyl) side chain into peptide backbones to modulate stability, activity, and bioavailability.
• Agrochemical Synthesis: Serves as a precursor in the development of new herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Academic & Industrial Research: Utilized in exploratory chemistry for developing new synthetic methodologies and studying structure-activity relationships (SAR).

Basic Information

Product Name	(3-Bromo-1-Methylpropyl)Carbamic Acid tert-Butyl Ester
CAS No.	128412-15-7
Molecular Formula	C9H18BrNO2
Molecular Weight	252.15 g/mol
Synonyms	tert-Butyl (3-bromo-1-methylpropyl)carbamate; N-Boc-3-bromo-1-methylpropylamine; Boc-3-bromo-1-methylpropylamine; 1-Methyl-3-bromopropylcarbamic acid tert-butyl ester; (3-Bromobutyl)carbamic acid tert-butyl ester (common misnomer); N-(tert-Butoxycarbonyl)-3-bromo-1-methylpropylamine; 3-Bromo-1-methylpropylamine, N-Boc protected; BOC-3-Bromo-1-methylpropylamine
EINECS	Contact for details

Quality Control

Our (3-Bromo-1-Methylpropyl)Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance in cGMP and ISO 9001 environments for pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere (e.g., nitrogen or argon) to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.