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6-Methyl-6,11-Dihydro-11-((N,n-Dimethylamino)Acetyl)Dibenzo(C,F)-(1,2,5)-Thiadiazepine 5,5-Dioxide CAS NO 128377-70-8


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CAS No.:128377-70-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

6-Methyl-6,11-Dihydro-11-((N,n-Dimethylamino)Acetyl)Dibenzo(C,F)-(1,2,5)-Thiadiazepine 5,5-Dioxide is a high-purity, advanced pharmaceutical intermediate characterized by its unique dibenzo-thiadiazepine dioxide core structure. This compound is of significant commercial interest for its role in the synthesis of novel therapeutic agents, particularly in central nervous system (CNS) research. It is primarily sought by pharmaceutical R&D departments and fine chemical manufacturers engaged in developing next-generation medications.

Application

  • Key Intermediate in Pharmaceutical Synthesis: Serves as a critical building block for the development of novel psychotropic and neuroactive drug candidates.
  • Research & Development (R&D): Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization processes.
  • Preclinical Studies: Employed in the production of compounds for pharmacological profiling and toxicology assessments.
  • Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
  • Reference Standard: Can be utilized as an analytical standard for quality control and method development in API manufacturing.

Basic Information

Product Name 6-Methyl-6,11-Dihydro-11-((N,n-Dimethylamino)Acetyl)Dibenzo(C,F)-(1,2,5)-Thiadiazepine 5,5-Dioxide
CAS No. 128377-70-8
Molecular Formula C19H19N3O3S
Molecular Weight 369.44 g/mol
Synonyms 11-[(Dimethylamino)acetyl]-6-methyl-6,11-dihydrodibenzo[c,f][1,2,5]thiadiazepine 5,5-dioxide; 6-Methyl-6,11-dihydro-11-[(dimethylamino)acetyl]dibenzo[c,f][1,2,5]thiadiazepine 5,5-dioxide; L-687,384; L 687384; L687384; (6R,11R)-6-Methyl-6,11-dihydro-11-[(dimethylamino)acetyl]dibenzo[c,f][1,2,5]thiadiazepine 5,5-dioxide (for specific stereoisomer)
EINECS Contact for details

Quality Control

Our production of 6-Methyl-6,11-Dihydro-11-((N,n-Dimethylamino)Acetyl)Dibenzo(C,F)-(1,2,5)-Thiadiazepine 5,5-Dioxide adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your internal specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to reference spectrum
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm
Specific Optical Rotation Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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