Description

L-Alanine, n-[(2-Propenyloxy)Carbonyl]-, Methyl Ester is a specialized, high-purity chemical building block used in advanced organic synthesis. This compound is valued for its role as a protected amino acid derivative, enabling precise molecular construction. It is primarily required by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for applications such as peptide synthesis and the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediates: A key building block in the synthesis of complex peptides and peptidomimetics for drug discovery and development.
• Bioconjugation Chemistry: Used in the preparation of protein-drug conjugates and other bioconjugates due to its reactive allyloxycarbonyl (Alloc) protecting group.
• Solid-Phase Peptide Synthesis (SPPS): Serves as a protected L-alanine derivative for the controlled, sequential assembly of peptide chains.
• Chemical Biology Research: Employed in the study of enzyme mechanisms and the development of activity-based probes.
• Agrochemical Synthesis: Can be utilized as an intermediate in the production of specialized, bioactive crop protection agents.
• Material Science: A potential monomer or modifier for creating functional polymers with specific chiral or bioactive properties.

Basic Information

Product Name	L-Alanine, n-[(2-Propenyloxy)Carbonyl]-, Methyl Ester
CAS No.	128369-70-0
Molecular Formula	C8H13NO4
Molecular Weight	187.19 g/mol
Synonyms	N-Alloc-L-alanine methyl ester; Methyl N-(allyloxycarbonyl)-L-alaninate; L-Alanine, N-[(2-propen-1-yloxy)carbonyl]-, methyl ester; (S)-Methyl 2-((allyloxycarbonyl)amino)propanoate; Alloc-L-Ala-OMe; N-(Allyloxycarbonyl)-L-alanine methyl ester; Methyl (S)-2-(((allyloxy)carbonyl)amino)propanoate; N-[(Allyloxy)carbonyl]-L-alanine methyl ester
EINECS	Contact for details

Quality Control

Our L-Alanine, n-[(2-Propenyloxy)Carbonyl]-, Methyl Ester is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification, to meet the stringent requirements of pharmaceutical R&D and production. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.