Description

[R-(R*,S*)]-(-)-n-(1-Phenylethyl)-1-Azabicyclo[2.2.2]Octan-3-Amine Dihydrochloride is a high-purity, chiral amine derivative of the azabicyclo[2.2.2]octane scaffold. This compound matters as a sophisticated pharmaceutical intermediate and research chemical for developing novel active ingredients, particularly in neuroscience and receptor-targeted therapies. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical synthesis industries.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex drug candidates, especially those targeting neurological pathways.
• Asymmetric Synthesis Catalyst/Chiral Auxiliary: Utilized in stereoselective synthesis to induce chirality in target molecules.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies in drug discovery programs.
• Ligand for Receptor Studies: Used in biochemical assays to study interactions with specific biological receptors.
• Reference Standard: Employed as an analytical standard for quality control and method development in analytical laboratories.
• Fine Chemical Synthesis: Incorporated into the synthesis of specialty chemicals, agrochemicals, and advanced materials requiring specific stereochemistry.

Basic Information

Product Name	[R-(R*,S*)]-(-)-n-(1-Phenylethyl)-1-Azabicyclo[2.2.2]Octan-3-Amine Dihydrochloride
CAS No.	128311-06-8
Molecular Formula	C15H24Cl2N2
Molecular Weight	303.27 g/mol
Synonyms	(-)-N-(1-Phenylethyl)-3-aminoquinuclidine dihydrochloride; (R,S)-(-)-N-(1-Phenylethyl)-3-aminoquinuclidine dihydrochloride; 3-[(1R)-1-Phenylethylamino]quinuclidine dihydrochloride; 1-Azabicyclo[2.2.2]octan-3-amine, N-(1-phenylethyl)-, dihydrochloride, (R-(R*,S*))-(-)-; (-)-N-(α-Methylbenzyl)-3-aminoquinuclidine dihydrochloride; Quinuclidine, 3-[(1R)-1-phenylethylamino]-, dihydrochloride; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our [R-(R*,S*)]-(-)-n-(1-Phenylethyl)-1-Azabicyclo[2.2.2]Octan-3-Amine Dihydrochloride is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and fine chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.