Description

(6As)-5-Chloro-9-[(2S,3R)-3-Hydroxy-2-Methyl-1-Oxobutyl]-6Aα-Methyl-3-[(1E,3S)-3-Methyl-1-Pentenyl]-6H-Furo[2,3-H]-2-Benzopyran-6,8(6Ah)-Dione is a complex, high-purity organic compound with a defined stereochemistry, serving as a critical advanced pharmaceutical intermediate or research chemical. Its intricate molecular architecture makes it a valuable building block for the synthesis of novel active pharmaceutical ingredients (APIs) and for probing specific biochemical pathways. This compound is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of potential drug candidates, particularly in oncology and anti-infective research.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Process Chemistry Development: Serves as a reference standard or starting material for scaling up and optimizing synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Biochemical Research: Potential use as a tool compound or inhibitor in enzymatic assays and target validation studies due to its specific stereochemical configuration.
• Custom Synthesis & Contract Manufacturing: Supplied to clients requiring bespoke, high-complexity molecules for proprietary development programs.
• Academic Research: Employed in university and institutional labs for advanced organic synthesis methodology development and chemical biology projects.

Basic Information

Product Name	(6As)-5-Chloro-9-[(2S,3R)-3-Hydroxy-2-Methyl-1-Oxobutyl]-6Aα-Methyl-3-[(1E,3S)-3-Methyl-1-Pentenyl]-6H-Furo[2,3-H]-2-Benzopyran-6,8(6Ah)-Dione
CAS No.	128252-98-2
Molecular Formula	C24H25ClO6
Molecular Weight	444.91 g/mol
Synonyms	5-Chloro-9-[(2S,3R)-3-hydroxy-2-methyl-1-oxobutyl]-6Aα-methyl-3-[(1E,3S)-3-methyl-1-pentenyl]-6H-furo[2,3-h]-2-benzopyran-6,8(6Ah)-dione; (6aS)-5-Chloro-9-[(2S,3R)-3-hydroxy-2-methyl-1-oxobutyl]-6a-methyl-3-[(1E,3S)-3-methyl-1-pentenyl]-6H-furo[2,3-h]-2-benzopyran-6,8(6aH)-dione; Furobenzopyrandione derivative; CAS 128252-98-2; 128252-98-2.
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and traceability. Quality is verified through comprehensive analytical techniques including HPLC, chiral analysis, NMR, and mass spectrometry to confirm identity, purity, and stereochemical integrity. A detailed Certificate of Analysis (COA) is provided with each shipment, and we support customer audits and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. The compound may be light-sensitive and/or hygroscopic; handle and store under an inert atmosphere if recommended for long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.