Description

4-Fluoro-3-Trifluoromethylphenylthiourea is a specialized fluorinated thiourea derivative, a key building block in advanced organic synthesis. This compound is valued for its unique trifluoromethyl and fluorine substituents, which impart desirable properties like enhanced metabolic stability and lipophilicity to target molecules. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging the bioactivity of the thiourea moiety.
• Material Science: Serves as a monomer or additive in the creation of specialty polymers with specific fluorine-related properties like chemical resistance or low surface energy.
• Chemical Synthesis: Acts as a versatile reagent for introducing the 4-fluoro-3-trifluoromethylphenyl group into more complex molecular architectures.
• Ligand & Catalyst Development: Employed in the preparation of novel ligands for metal catalysis or in organocatalysis research.

Basic Information

Product Name	4-Fluoro-3-Trifluoromethylphenylthiourea
CAS No.	128143-17-9
Molecular Formula	C8H4F4N2S
Molecular Weight	236.19 g/mol
Synonyms	1-(4-Fluoro-3-(trifluoromethyl)phenyl)thiourea; N-(4-Fluoro-3-trifluoromethylphenyl)thiourea; 4-Fluoro-α,α,α-trifluoro-m-tolylthiourea; (4-Fluoro-3-trifluoromethylphenyl)thiourea; 4-Fluoro-3-trifluoromethylphenyl-thiourea; 4-Fluoro-3-trifluoromethyl-phenylthiourea; 4-Fluoro-3-(trifluoromethyl)phenylthiourea
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-Trifluoromethylphenylthiourea is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.