Description

Methyl-6-o-(Tert.-Butyldimethylsilyl)-2,3,4-Tri-o-Benzoyl-α-D-Glucopyranoside CAS NO 128142-70-1 is a sophisticated, multi-protected carbohydrate derivative designed for advanced synthetic chemistry. This compound is a critical protected intermediate, enabling precise and selective glycosylation reactions in the synthesis of complex oligosaccharides and glycoconjugates. It is essential for researchers and process chemists in pharmaceutical development, particularly for creating novel carbohydrate-based therapeutics, vaccines, and diagnostic agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of complex carbohydrate-based drugs, including antibiotics, antivirals, and anticancer agents.
• Glycobiology Research: Used in academic and industrial R&D to study glycosylation pathways and synthesize specific oligosaccharide structures for biological activity screening.
• Glycoconjugate Vaccine Development: Serves as a crucial precursor in the production of carbohydrate antigens conjugated to carrier proteins for next-generation vaccines.
• Process Chemistry: Employed in scalable synthetic routes where the tert-butyldimethylsilyl (TBDMS) and benzoyl protecting groups offer orthogonal deprotection strategies.
• Standards & Reference Materials: Supplied as a high-purity standard for analytical method development and quality control in carbohydrate chemistry.

Basic Information

Product Name	Methyl-6-o-(Tert.-Butyldimethylsilyl)-2,3,4-Tri-o-Benzoyl-α-D-Glucopyranoside
CAS No.	128142-70-1
Molecular Formula	C35H42O9Si
Molecular Weight	634.79 g/mol
Synonyms	Methyl 6-O-(tert-Butyldimethylsilyl)-2,3,4-tri-O-benzoyl-α-D-glucopyranoside; Methyl 2,3,4-Tri-O-benzoyl-6-O-tert-butyldimethylsilyl-α-D-glucopyranoside; α-D-Glucopyranoside, methyl 6-O-(1,1-dimethylethyl)dimethylsilyl-2,3,4-tribenzoate; TBDMS-protected methyl glucopyranoside tribenzoate; Methyl 6-TBDMS-2,3,4-tribenzoyl-α-D-glucoside
EINECS	Contact for details

Quality Control

This high-value synthetic intermediate is produced under strict quality control protocols to ensure batch-to-batch consistency and purity suitable for sensitive pharmaceutical applications. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.