Description

Benzeneethanimidamide, n-Hydroxy-3-(Trifluoromethyl) is a specialized trifluoromethyl-substituted benzimidamide derivative, a key intermediate in modern synthetic chemistry. Its value lies in its unique molecular scaffold, which combines a reactive amidoxime group with the electron-withdrawing and lipophilicity-enhancing trifluoromethyl moiety. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it serves as a critical building block for developing novel active ingredients with improved metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors, anti-inflammatory agents, and central nervous system (CNS) targeted therapies.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic materials with specific electronic or surface properties.
• Chemical Biology & Proteomics: Employed as a molecular probe or a tag in bioconjugation chemistry for studying protein interactions and cellular pathways.
• Organic Synthesis Building Block: Utilized in heterocyclic chemistry for constructing complex molecules like benzimidazoles, quinazolines, and other nitrogen-containing fused ring systems.

Basic Information

Product Name	Benzeneethanimidamide, n-Hydroxy-3-(Trifluoromethyl)
CAS No.	128104-39-2
Molecular Formula	C9H8F3N3O
Molecular Weight	231.18 g/mol
Synonyms	3-(Trifluoromethyl)benzamidoxime; N'-Hydroxy-3-(trifluoromethyl)benzenecarboximidamide; 3-(Trifluoromethyl)benzamidine, N-hydroxy-; Benzenecarboximidamide, N-hydroxy-3-(trifluoromethyl)-; Amidoxime, 3-(Trifluoromethyl)benz-; 3-Trifluoromethylbenzamidoxime; (Z)-N'-Hydroxy-3-(trifluoromethyl)benzenecarboximidamide
EINECS	Contact for details

Quality Control

Our production of Benzeneethanimidamide, n-Hydroxy-3-(Trifluoromethyl) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its nature as an easily oxidized compound, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.